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AZD5904

Cat. No. M14442

All AbMole products are for research use only, cannot be used for human consumption.

AZD5904 Structure
Size Price Availability Quantity
5mg USD 135 In stock
10mg USD 182 In stock
25mg USD 330 In stock
50mg USD 580 In stock
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Quality Control & Documentation
Biological Activity

AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat.

Chemical Information
Molecular Weight 252.29
CAS Number 618913-30-7
Form Solid
Solubility (25°C) DMSO 22.73 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yesica Garciafigueroa, et al. Neutrophil-Associated Inflammatory Changes in the Pre-Diabetic Pancreas of Early-Age NOD Mice

[2] Chrishan J A Ramachandra, et al. Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes

[3] M J Campbell, et al. Myeloperoxidase inhibitor AZD5904 enhances human sperm function in vitro

[4] Weidong Chai, et al. Inhibiting myeloperoxidase prevents onset and reverses established high-fat diet-induced microvascular insulin resistance

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Keywords: AZD5904 supplier, inhibitors, activators

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