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AZD-8529 mesylate is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
| Molecular Weight | 583.58 |
| Formula | C25H28F3N5O6S |
| CAS Number | 1314217-69-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 41.67 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
[1] Yoshiharu Uno. Intern Emerg Med. Camostat mesilate therapy for COVID-19
[2] Ferdi Schüth. Science. Making more from methane
[4] Sarika Jain, et al. Clin Cancer Res. Eribulin mesylate
[5] Timothy K Huyck, et al. Nat Rev Drug Discov. Eribulin mesylate
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