Free shipping on all orders over $ 500

AZA1

Cat. No. M27747

All AbMole products are for research use only, cannot be used for human consumption.

AZA1 Structure
Synonym:

Rac1/Cdc42-IN-1

Size Price Availability Quantity
5mg USD 280 In stock
10mg USD 440 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

AZA1 is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induces prostate cancer cells apoptosis and inhibits prostate cancer cells proliferation, migration and invasion.

Chemical Information
Molecular Weight 368.43
Formula C22H20N6
CAS Number 1071098-42-4
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Antony A Okumu, et al. Org Lett. Synthesis of the C1-C19 Domain of Azaspiracid-34

[2] M Pelin, et al. Toxicol Lett. Toxic equivalency factors (TEFs) after acute oral exposure of azaspiracid 1, -2 and -3 in mice

[3] Jane Kilcoyne, et al. Chem Res Toxicol. Epimers of azaspiracids: Isolation, structural elucidation, relative LC-MS response, and in vitro toxicity of 37-epi-azaspiracid-1

[4] Thierry Jauffrais, et al. Toxicon. Dissolved azaspiracids are absorbed and metabolized by blue mussels (Mytilus edulis)

[5] T Nomura, et al. Cancer Lett. In vivo diffusion chamber culture reduces the tumorigenicity of PCC4-aza1 teratocarcinoma cells

Related Ras Products
ZCL278

ZCL278 is a selective Cdc42 GTPase inhibitor with Kd of 11.4 μM.

Kobe0065

Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD, exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.

K-Ras(G12C) inhibitor 9

K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).

6H05 trifluoroacetate

6H05 is a selective and allosteric inhibitor of oncogenic K-Ras(G12C).

Salirasib

Salirasib is a potent competitive prenylated protein methyltransferase (PPMTase) inhibitor with Ki of 2.6 μM, which inhibits Ras methylation. Phase 2.

  Catalog
Abmole Inhibitor Catalog




Keywords: AZA1, Rac1/Cdc42-IN-1 supplier, Ras, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.