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AZ-PFKFB3-67 

Cat. No. M28820

All AbMole products are for research use only, cannot be used for human consumption.

AZ-PFKFB3-67  Structure

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Quality Control & Documentation
Biological Activity

AZ-PFKFB3-67 is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively.

Chemical Information
Molecular Weight 455.51
Formula C26H25N5O3
CAS Number 1704741-11-6
Form Solid
Solubility (25°C) DMSO ≥ 250 mg/mL
Storage Powder -20°C
References

[1] Besa Emini Veseli, et al. Int J Mol Sci. The PFKFB3 Inhibitor AZ67 Inhibits Angiogenesis Independently of Glycolysis Inhibition

Related PFKFB3 Products
PFK-015

PFK-015 is a potent and selective 6-phosphofructo-2-kinase (PFKFB3) inhibitor. PFK-015 inhibits recombinant PFKFB3 with an IC50 value of 110 nM and inhibits PFKFB3 activity in cancer cells with an IC50 value of 20 nM.

3PO

3PO is a novel small-molecule inhibitor of the PFKFB3 isozyme, attenuates the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines with IC50 of 1.4-24 μM.

PFK-158

PFK-158, also known as ACT-PFK-158, is a potent and selective inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) with potential antineoplastic activity.

  Catalog
Abmole Inhibitor Catalog




Keywords: AZ-PFKFB3-67  supplier, PFKFB3, inhibitors, activators

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