AZ-4217

Cat. No. M56804

All AbMole products are for research use only, cannot be used for human consumption.

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.

AZ-4217 is an inhibitor for β-site amyloid precursor protein cleavage enzyme 1 (BACE1), with IC50 of 160 pM in human SH-SY5Y cells.

Molecular Weight	476.54
Formula	C30H25FN4O
CAS Number	1383846-83-0
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

Related BACE Products
LY2886721 LY2886721 is an effective, selective, orally active inhibitor of beta-site amyloid precursor protein lyase 1 (BACE1) with an IC50 of 20.3 nM against recombinant human BACE1. LY2886721 showed higher selectivity for BACE1 than cathepsin D, pepsin and renin, but lacked selectivity for BACE2 (IC50 was 10.2 nM). LY2886721 crosses the blood-brain barrier and can be used to study Alzheimer's disease.
AZD3839 AZD3839 is a potent and selective inhibitor of human BACE1 with K_i of 26.1 nM.
Lanabecestat Lanabecestat (AZD3293, LY3314814) is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor.
Eslicarbazepine Acetate Eslicarbazepine acetate is an antiepileptic drug.
Verubecestat (MK-8931) Verubecestat (MK-8931) is an orally active, high-affinity (beta-secretase 1) BACE1 and BACE2 inhibitor, with Ki values of 2.2 nM and 0.38 nM, respectively.

Catalog