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AZ-33 (LDHA-IN-4) is a potent lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.5 μM.
| Molecular Weight | 497.56 |
| Formula | C25H27N3O6S |
| CAS Number | 1370290-34-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related LDH Products |
|---|
| Galloflavin
Galloflavin is a lactate dehydrogenase inhibitor; impairs aerobic glycolysis. |
| GSK2837808A
GSK2837808A is a potent, selective lactate dehydrogenase A (LDHA) inhibitor with IC50s of 2.6 and 43 nM for hLDHA and hLDHB, respectively. |
| NHI-2
NHI-2 is an inihbitor of Lactate dehydrogenase-A (LDH-A, LDHA), a key enzyme necessary to sustain glycolysis, the major pathway used by many cancer cells for cell growth and proliferation (the Warburg effect). |
| GNE-140 racemate
GNE-140 racemate is a racemic mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is also a potent lactate dehydrogenase A (LDHA) inhibitor. |
| (R)-GNE-140
(R)-GNE-140 is a selective inhibitor of LDHA and LDHB with IC50 of 3 nM and 5 nM, respectively. (R)-GNE-140 is 18 times more potent than its S-type isomer. |
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