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Avicularin

Cat. No. M4761

All AbMole products are for research use only, cannot be used for human consumption.

Avicularin Structure
Size Price Availability Quantity
1mg USD 65 In stock
5mg USD 125 In stock
10mg USD 200 In stock
20mg USD 300 In stock
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Quality Control & Documentation
Biological Activity

Avicularin is a bioactive flavonoid found in a variety of plants. It has anti-inflammatory, anti-allergy, anti-oxidation, liver protection, anti-tumor and other effects. Avicularin inhibits NF-κB (p65), COX-2 and PPAR-γ activities. In LPS-stimulated RAW 264.7 macrophages, Avicularin produces anti-inflammatory activity by inhibiting the ERK signaling pathway.

Chemical Information
Molecular Weight 434.35
Formula C20H18O11
CAS Number 572-30-5
Form Solid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Nikita Patil Samant, et al. Avicularin Attenuates Memory Impairment in Rats with Amyloid Beta-Induced Alzheimer's Disease

[2] Zi-Ling Zou, et al. Avicularin suppresses cartilage extracellular matrix degradation and inflammation via TRAF6/MAPK activation

[3] Joy A Amadi, et al. Lettuce-avicularin treatment reverses insulin resistance through stimulation of glycolytic kinases and insulin signaling molecules

[4] Zhentao Zhang, et al. Avicularin Reduces the Expression of Mediators of Inflammation and Oxidative Stress in Bradykinin-Treated MG-63 Human Osteoblastic Osteosarcoma Cells

[5] Zhimin Wang, et al. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF‑κB/COX‑2/PPAR‑γ activities

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Keywords: Avicularin supplier, COX, inhibitors, activators

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