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Aureobasidin A (AbA) is a cyclic ester peptide antibiotics which derived from filamentous fungi, and it has strong antifungal ability. Aureobasidin A (AbA) inhibits the activity of inositol phosphorylceramide (IPC) synthetase, which is dependent on fungal growth, and interferes with sphingolipid synthesis, thereby further killing the strain.
mSystems. 2022 Oct 20;e0053922.
Systematic Metabolic Profiling Identifies De Novo Sphingolipid Synthesis as Hypha Associated and Essential for Candida albicans Filamentation
Aureobasidin A purchased from AbMole
| Molecular Weight | 1101.43 |
| Formula | C60H92N8O11 |
| CAS Number | 127785-64-2 |
| Solubility (25°C) | Soluble in methanol |
| Storage | 4°C, protect from light, dry, sealed |
[2] Adriana M Rauseo, et al. Hope on the Horizon: Novel Fungal Treatments in Development
[4] Sabrina Sonda, et al. Inhibitory effect of aureobasidin A on Toxoplasma gondii
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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