ATM Inhibitor-10

Cat. No. M55918

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ATM Inhibitor-10, a 3-quinoline carboxamide, is a highly selective and orally active ATM inhibitor (IC50: 0.6 nM).

Molecular Weight	434.47
Formula	C23H23FN6O2
CAS Number	1941214-06-7
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

Related ATM/ATR Products
KU-55933 KU-55933 is a cell-permeable ATP-competitive inhibitor of ATM (IC50 = 13 nM; Ki = 2.2 nM) with selectivity over other PIKK family kinases (IC50 = 2.5, 9.3, 16.6 μM for DNAPK, mTOR, PI 3-K, respectively; IC50 > 100 μM for PI 4-K and ATR).
KU-60019 KU-60019 is a potent ATM kinase inhibitor with IC50 of 6.3 nM.
VE-821 VE-821 is a highly selective and potent ATR inhibitor with IC50 of 26 nM.
ETP-46464 ETP-46464 is a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα and ATM with IC50 of 0.6, 14, 36, 170 and 545 nM, respectively.
CP-466722 Cp-466722 is a reversible ATM inhibitor with IC50 value of 4.1 μM, but has no effect on PI3K, PIKK family proteins.

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