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Asperosaponin-VI

Cat. No. M4705

All AbMole products are for research use only, cannot be used for human consumption.

Asperosaponin-VI Structure
Synonym:

Akebia saponin D

Size Price Availability Quantity
2mg USD 25 In stock
5mg USD 35 In stock
10mg USD 55 In stock
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Quality Control & Documentation
Biological Activity

Asperosaponin-VI induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB.

Chemical Information
Molecular Weight 929.1
Formula C47H76O18
CAS Number 39524-08-8
Solubility (25°C) Water 90 mg/mL
DMSO 25 mg/mL
Storage -20°C, protect from light, sealed
References

[1] Fangping Chen, et al. Synergy effects of Asperosaponin VI and bioactive factor BMP-2 on osteogenesis and anti-osteoclastogenesis

[2] Jinqiang Zhang, et al. Asperosaponin VI inhibits LPS-induced inflammatory response by activating PPAR-γ pathway in primary microglia

[3] Jinqiang Zhang, et al. The antidepressant effects of asperosaponin VI are mediated by the suppression of microglial activation and reduction of TLR4/NF-κB-induced IDO expression

[4] Dan Ma, et al. Asperosaponin VI Injection Enhances Orthodontic Tooth Movement in Rats

[5] Xingpo Ding, et al. Asperosaponin VI stimulates osteogenic differentiation of rat adipose-derived stem cells

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Keywords: Asperosaponin-VI, Akebia saponin D supplier, Caspase, inhibitors, activators

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