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ASP4132

Cat. No. M13362

All AbMole products are for research use only, cannot be used for human consumption.

ASP4132 Structure
Size Price Availability Quantity
1mg USD 60 In stock
5mg USD 140 In stock
10mg USD 230 In stock
25mg USD 420 In stock
50mg USD 700 In stock
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Biological Activity

ASP4132 is an orally active, potent AMPK activator with an EC50 of 18 nM and anticancer activity that promotes tumor regression in a xenograft mouse model of breast cancer.

Chemical Information
Molecular Weight 764.87
Formula C39H43F3N6O5S
CAS Number 1640294-30-9
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, dry, sealed
References

[1] Filip Janku, et al. Invest New Drugs. First-in-human evaluation of the novel mitochondrial complex I inhibitor ASP4132 for treatment of cancer

[2] Ying-Chen Xia, et al. Cell Death Dis. AMPK activation by ASP4132 inhibits non-small cell lung cancer cell growth

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Keywords: ASP4132 supplier, AMPK, inhibitors, activators

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