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ASP2905 

Cat. No. M30617

All AbMole products are for research use only, cannot be used for human consumption.

ASP2905  Structure

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Biological Activity

ASP2905 is a potent and selective potassium channel Kv12.2 inhibitor encoded by the Kcnh3/BEC1 gene. ASP2905 can cross the blood-brain barrier and has antipsychotic activities.

Chemical Information
Molecular Weight 388.4
Formula C20H17FN8
CAS Number 792184-90-8
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Keisuke Fukunaga, et al. J Am Chem Soc. Small-Molecule Aptamer for Regulating RNA Functions in Mammalian Cells and Animals

[2] Shinji Takahashi, et al. Behav Brain Res. ASP2905, a specific inhibitor of the potassium channel Kv12.2 encoded by the Kcnh3 gene, is psychoactive in mice

[3] Shinji Takahashi, et al. PLoS One. The KCNH3 inhibitor ASP2905 shows potential in the treatment of attention deficit/hyperactivity disorder

[4] Shinji Takahashi, et al. Eur J Pharmacol. Neurochemical and neuropharmacological characterization of ASP2905, a novel potent selective inhibitor of the potassium channel KCNH3

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  Catalog
Abmole Inhibitor Catalog




Keywords: ASP2905  supplier, Potassium Channel, inhibitors, activators

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