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ASP2535 is a potent, orally bioavailable, selective, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor. ASP2535 can improve cognitive impairment in animal models of schizophrenia and Alzheimer's disease.
| Molecular Weight | 382.42 |
| Formula | C22H18N6O |
| CAS Number | 374886-51-8 |
| Form | Solid |
| Storage | Powder -20°C |
| Related GlyT Products |
|---|
| Bitopertin
Bitopertin (RG1678,RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells. |
| LY 2365109 hydrochloride
LY 2365109 hydrochloride is a potent and selective GlyT1 inhibitor. |
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Products are for research use only. Not for human use. We do not sell to patients.
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