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ASN007

Cat. No. M31230

All AbMole products are for research use only, cannot be used for human consumption.

ASN007 Structure
Size Price Availability Quantity
5mg USD 150 In stock
10mg USD 250 In stock
25mg USD 530 In stock
50mg USD 920 In stock
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Quality Control & Documentation
Biological Activity

ASN007 (ERK-IN-3) is a potent and orally active inhibitor of ERK. ASN007 inhibits ERK1/2 with low single-digit nM IC50 values. ASN007 can be used for the research of cancers driven by RAS mutations.

Chemical Information
Molecular Weight 473.93
Formula C22H25ClFN7O2
CAS Number 2055597-12-9
Form Solid
Solubility (25°C) DMSO >100 mg/mL (Need ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bo Mi Ku, et al. Invest New Drugs. ERK inhibitor ASN007 effectively overcomes acquired resistance to EGFR inhibitor in non-small cell lung cancer

[2] Ana Portelinha, et al. Cell Rep Med. ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

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Keywords: ASN007 supplier, ERK, inhibitors, activators

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