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ASK120067 is the third generation EGFR-TKI for non-small cell lung cancer (NSCLC) studies and is an effective oral EGFRT790M inhibitor (IC50 = 0.3 nM) with EGFRWT selectivity (IC50 = 6.0 nM).
| Molecular Weight | 546.07 |
| Formula | C29H32ClN7O2 |
| CAS Number | 1934259-00-3 |
| Solubility (25°C) | DMSO : 41.67 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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