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Asfotase alfa

Cat. No. M24565

All AbMole products are for research use only, cannot be used for human consumption.

Asfotase alfa Structure
Synonym:

ENB-0040

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Quality Control & Documentation
Biological Activity

Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2−/− knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP).

Chemical Information
CAS Number 1174277-80-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] No authors listed. Aust Prescr. Asfotase alfa for hypophosphatasia

[2] No authors listed. Asfotase Alfa (Strensiq) [Internet]

[3] C Hofmann, et al. Drugs Today (Barc). Asfotase alfa: enzyme replacement for the treatment of bone disease in hypophosphatasia

[4] Lesley J Scott. BioDrugs. Asfotase Alfa in Perinatal/Infantile-Onset and Juvenile-Onset Hypophosphatasia: A Guide to Its Use in the USA

[5] Lesley J Scott. Drugs. Asfotase Alfa: A Review in Paediatric-Onset Hypophosphatasia

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Keywords: Asfotase alfa, ENB-0040 supplier, inhibitors, activators

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