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ARN1468 

Cat. No. M28296

All AbMole products are for research use only, cannot be used for human consumption.

ARN1468  Structure

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Quality Control & Documentation
Biological Activity

ARN1468 (compound 5) is an orally active and potent serpins inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC50 values of 8.64, 19.3, 11.2, and 6.27 μM.

Chemical Information
Molecular Weight 354.33
Formula C16H17F3N4O2
CAS Number 1381459-14-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Arianna Colini Baldeschi, et al. J Med Chem. Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance

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  Catalog
Abmole Inhibitor Catalog




Keywords: ARN1468  supplier, inhibitors, activators

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