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ARN14494 is a potent and selective serine palmitoyltransferase (SPT) inhibitor, with an IC50 of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from β-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti-apoptosis, and anti-inflammation. ARN14494 can be used for Alzheimer’s disease research.
| Molecular Weight | 424.54 |
| Formula | C24H32N4O3 |
| CAS Number | 1037837-27-6 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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