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Aripiprazole lauroxil, an N-acyloxymethyl?proagent?of?aripiprazole, is a?Long-acting injectable (LAI)?typical antipsychotic for?schizophrenia. Aripiprazole lauroxil is cleaved by body’s enzyme esterase to N-hydroxymethyl aripiprazole (plus lauric acid) and then to aripiprazole (plus formaldehyde), no toxicity.
| Molecular Weight | 660.71 |
| Formula | C36H51Cl2N3O4 |
| CAS Number | 1259305-29-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 8.33 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] James E Frampton. Drugs. Aripiprazole Lauroxil: A Review in Schizophrenia
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