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ARD-69 

Cat. No. M29505

All AbMole products are for research use only, cannot be used for human consumption.

ARD-69  Structure

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Quality Control & Documentation
Biological Activity

ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression.

Chemical Information
Molecular Weight 1129.82
Formula C62H74ClFN8O7S
CAS Number 2316837-10-0
Form Solid
Solubility (25°C) DMSO ≥ 200 mg/mL
Storage -20°C, protect from light, sealed
References

[1] Xin Han, et al. J Med Chem. Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer

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  Catalog
Abmole Inhibitor Catalog




Keywords: ARD-69  supplier, Androgen Receptor, inhibitors, activators

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