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ARCC-4 is based on PROTAC technology, a nanomolar grade androgen receptor (AR) degrader D50 The value is 5 nM. ARCC-4 is an AR PROTAC recruited by von Hippel-Lindau (VHL) based on enzalutamide. ARCC-4 effectively degrades AR mutations associated with antiandrogen studies.
| Molecular Weight | 1024.18 |
| Formula | C53H56F3N7O7S2 |
| CAS Number | 1973403-00-7 |
| Solubility (25°C) | DMSO ≥ 150 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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