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Arbutin

Cat. No. M4599

All AbMole products are for research use only, cannot be used for human consumption.

Arbutin Structure
Synonym:

p-Arbutin; β-Arbutin

Size Price Availability Quantity
100mg USD 35 In stock
500mg USD 50 In stock
1g USD 55 In stock
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Quality Control & Documentation
Biological Activity

Arbutin (β -arbutin) is a natural polyphenol isolated from the bear fruit plant Arctostaphylos uvaursi with antioxidant, anti-inflammatory and anti-tumor properties. It is a competitive inhibitor of tyrosinase in melanocytes, with a Kiapp value of 1.42 mM for monopholase. The value of p-diphenol enzyme Kiapp was 0.9 mM. Arbutin is also used as a bleaching agent.

Chemical Information
Molecular Weight 272.25
Formula C12H16O7
CAS Number 497-76-7
Solubility (25°C) DMSO 45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nasiruddin Nalban, et al. Cardiovasc Toxicol. Arbutin Attenuates Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting TLR-4/NF-κB Pathway in Mice

[2] Liyan Jiang, et al. Int J Mol Med. Investigation of the pro-apoptotic effects of arbutin and its acetylated derivative on murine melanoma cells

[3] Antonio Garcia-Jimenez, et al. PLoS One. Action of tyrosinase on alpha and beta-arbutin: A kinetic study

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Keywords: Arbutin, p-Arbutin; β-Arbutin supplier, inhibitors, activators

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