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AR-C 102222 is a inducible nitric oxide synthase (iNOS) inhibitor; selective for iNOS over eNOS (IC50 values are 0.037 and >100 μM for iNOS and eNOS respectively). Exhibits antinociceptive and anti-inflammatory activity in rodent pain models.
| Molecular Weight | 418.83 |
| Formula | C19H16F2N6O.HCl |
| CAS Number | 253771-21-0 |
| Solubility (25°C) | DMSO 41.86 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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