Free shipping on all orders over $ 500

Apicidin

Cat. No. M2400

All AbMole products are for research use only, cannot be used for human consumption.

Apicidin  Structure
Synonym:

OSI 2040

Size Price Availability
1mg USD 250 Out of stock
5mg USD 710 Out of stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Apicidin is a potent nonselective HDAC inhibitor with IC50 of 0.7 nM. Apicidin is a fungal metabolite, as well as a histone deacetylase inhibitor. Antiangiogenic and anti-invasive; Apicidin not only blocks proliferation of human stomach and breast cancer cells, but also induces apoptosis and autophagy in human oral squamous carcinoma cells.

Chemical Information
Molecular Weight 623.78
Formula C34H49N5O6
CAS Number 183506-66-3
Solubility (25°C) DMSO 20 mg/mL
Storage Powder -20°C
References

[1] Han, et al. Cancer Res. Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin.

[2] Darkin-Rattray, et al. Proc Natl Acad Sci U S A. Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase.

Related HDAC Products
SIS17

SIS17 is a histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM.

Belinostat

Belinostat (PXD101) is a novel HDAC inhibitor with an IC50 of 27 nM.

CUDC-101

CUDC-101 is a potent multitargeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively.

Givinostat hydrochloride monohydrate

ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively.

Niltubacin

Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6.

  Catalog
Abmole Inhibitor Catalog




Keywords: Apicidin , OSI 2040 supplier, HDAC, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.