All AbMole products are for research use only, cannot be used for human consumption.
Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM.
Neurochem Int. 2024 Oct 19;Nov:180:105885.
Apelin regulates mitochondrial dynamics by inhibiting Mst1-JNK-Drp1 signaling pathway to reduce neuronal apoptosis after spinal cord injury
Apelin-13 TFA purchased from AbMole
| Molecular Weight | 1664.85 |
| Formula | C71H112F3N23O18S |
| CAS Number | 217082-58-1 (free base) |
| Solubility (25°C) | Water 90 mg/mL |
| Storage | -20°C, dry, sealed |
| Related Apelin Receptor Products |
|---|
| ML221
ML221 is an Apelin (APJ) antagonist and inhibits apelin-13-mediated activation of APJ. IC50 values of cAMP and β -Arrestin were 0.70 μM and 1.75 μM, respectively. EC80 values were all 10 nM. |
| (Glp1)-Apelin-13 human, bovine
(Glp1)-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. |
| Apelin-36(rat, mouse) TFA
Apelin-36(rat, mouse) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. |
| Elabela(19-32)
Elabela(19-32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart. |
| Elabela(19-32) TFA
Elabela(19-32) TFA is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) TFA activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) TFA induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
