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AP20187

Cat. No. M13547

All AbMole products are for research use only, cannot be used for human consumption.

AP20187 Structure
Synonym:

B/B Homodimerizer

Size Price Availability Quantity
5mg USD 280 In stock
10mg USD 430 In stock
25mg USD 720 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions.

Chemical Information
Molecular Weight 1482.75
CAS Number 195514-80-8
Solubility (25°C) Ethanol 100 mg/mL
DMSO ≥ 57 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mikolaj Ogrodnik, et al. Aging Cell. Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice

[2] Xiaobing Yu, et al. Nat Commun. Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

[3] Mikolaj Ogrodnik, et al. Cell Metab. Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

[4] Darren J Baker, et al. Nature. Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

[5] Darren J Baker, et al. Nature. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

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Keywords: AP20187, B/B Homodimerizer supplier, inhibitors, activators

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