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Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18,0.70,1.40,44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively.
| Molecular Weight | 299.24 |
| Formula | C14H9N3O5 |
| CAS Number | 2364493-24-1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Huei-Mei Hsieh, et al. Appl Microbiol Biotechnol. Medicinal components in Termitomyces mushrooms
[3] Bernd Becker, et al. ACS Chem Biol. Aminoglycoside antibiotics in the 21st century
[4] Mark C Bagley, et al. Chem Rev. Thiopeptide antibiotics
[5] Julián Palomino, et al. Enferm Infecc Microbiol Clin. [Aminoglycosides]
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