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CD3 is an important marker of T cells, it is composed of five polypeptide chains: γ, δ, ε, ζ, and η. Mononuclear cells isolated from peripheral blood, bone marrow or cord blood can be cultured for a certain period of time in the presence of CD3 monoclonal antibodies and a variety of cytokines to obtain CIK (Cytokine-induced Killer) cells with tumor cell killing activity. The transmembrane region of the CD3 molecule is connected to the transmembrane region of the two peptide chains of the TCR through a salt bridge to form a TCR-CD3 complex, which jointly participates in the recognition of antigens by T cells. The activation signal generated by TCR recognition antigen is transduced into T cells by CD3.
| Solubility (25°C) | Water Saline PBS |
| Storage | 2-8°C for short term, -20°C for long term |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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