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Expression host: CHO cells
Purity: > 95%. Sds-page gel and HIGH performance liquid chromatography were used
Endotoxin: < 0.01 EU/μg
Storage and stability: stored at 2~8℃, valid for 24 months. In case of separate packaging, store in -20℃ storage period of 6 months, -80℃ storage period of 12 months, avoid repeated freeze-thaw.
Bioactivity: CD16 is FcγR ⅲ, a glycoprotein with a molecular weight of 50-70kD, a member of Ig superfamily, known to be involved in antigen-dependent cytotoxicity (ADCC). The most significant feature of CD16 is that the cleavage triggered by membrane receptors is performed by NK cells. CD16 acts as a low affinity receptor for the Fc portion of some IgG, binding to the Fcε -associated receptor I (εRI of Fc) γ chain of CD3ζ and co-participates in signal transduction. NK cell CD16 directly leads to an increase in intracellular Ca+ levels and a cascade of biochemical reactions similar to T cell receptor activation.
| Storage | 2-8℃ |
[5] Y W Huang, et al. Stem Cells. Immunotherapy of multiple myeloma
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Products are for research use only. Not for human use. We do not sell to patients.
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