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ANR 94

Cat. No. M6445

All AbMole products are for research use only, cannot be used for human consumption.

ANR 94 Structure

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Quality Control & Documentation
Biological Activity

ANR 94 is a adenosine A2A receptor (AA2AR) antagonist (Ki values are 643 and 46 nM for rat and human AA2ARs respectively). Most active AA2AR antagonist for human receptors. Displays activity in the treatment of Parkinson's disease in vivo; improves parkinsonian motor deficits and tremors. Exhibits neuroprotective and anti-inflammatory effects.

Chemical Information
Molecular Weight 207.23
Formula C9H13N5O
CAS Number 634924-89-3
Solubility (25°C) DMSO 10.36 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chang, et al. J Pharmacol Exp Ther. Tachykinin receptor subtypes in the isolated guinea pig heart and their role in mediating responses to neurokinin A.

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Keywords: ANR 94 supplier, Adenosine Receptor, inhibitors, activators

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