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AMXT-1501 tetrahydrochloride is an orally active polyamine transport inhibitor. AMXT-1501 blocks tumor growth in immunocompetent mice, but not T cell-deficient thymic nude mice. DFMO and AMXT-1501 jointly induce caspase-3-mediated apoptosis of NB cells.
| Molecular Weight | 714.77 |
| Formula | C32H72Cl4N6O2 |
| Solubility (25°C) | Water ≥ 60 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
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