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Amrinone (Inamrinone) is a positive inotropic-vasodilator agent. Amrinone is a selective phosphodiesterase III inhibitor that increases cyclic adenosine monophosphate by preventing its breakdown. Amrinone is also an orally active, non-glycosidic and non-catecholamine cardiotonic agent.
| Molecular Weight | 187.2 |
| Formula | C10H9N3O |
| CAS Number | 60719-84-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 16.67 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] M P Kullberg, et al. Clin Pharmacol Ther. Amrinone metabolism
[2] J E Wynands. J Cardiothorac Anesth. Amrinone: is it the inotrope of choice?
[3] J H Levy, et al. J Cardiothorac Anesth. Amrinone: pharmacokinetics and pharmacodynamics
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