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Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor with a Ki of 18.6 nM. Amodiaquine dihydrochloride is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect.
| Molecular Weight | 428.78 |
| CAS Number | 69-44-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL Water 50 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
[1] Abdullahi Tsanni. Nature. African scientists race to test COVID drugs - but face major hurdles
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