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AM 6545 is a high affinity and selective CB1 antagonist (Ki = 3.3 nM). Exhibits >100-fold selectivity for CB1 over CB2 receptors. Improves glucose homeostasis, reverses hepatic steatosis and reduces body weight in diet-induced obese mice. Orally available and non-brain penetrant.
| Molecular Weight | 556.46 |
| Formula | C26H23Cl2N5O3S |
| CAS Number | 1245626-05-4 |
| Solubility (25°C) | DMSO 11.13 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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| AM-2201
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Products are for research use only. Not for human use. We do not sell to patients.
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