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αvβ1 integrin-IN-2

Cat. No. M41629

All AbMole products are for research use only, cannot be used for human consumption.

αvβ1 integrin-IN-2 Structure

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Quality Control & Documentation
Biological Activity

αvβ1 integrin-IN-2 is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM, and 33 nM, respectively.

Chemical Information
Molecular Weight 506.64
Formula C29H38N4O4
CAS Number 2234874-68-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] R J Slack et al. Nat Rev Drug Discov. Emerging therapeutic opportunities for integrin inhibitors

[2] Seung-Jun Lee et al. J Clin Invest. Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction

[3] Alexandra Mousset et al. Cancer Cell. Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation

[4] Yasuo Oguri et al. Cell. CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling

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Keywords: αvβ1 integrin-IN-2 supplier, Integrin, inhibitors, activators

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