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Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor.
| Molecular Weight | 342.43 |
| Formula | C17H30N2O5 |
| CAS Number | 88321-09-9 |
| Solubility (25°C) | DMSO 60 mg/mL Ethanol 25 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] E Satoyoshi. Therapeutic trials on progressive muscular dystrophy
| Related Cathepsin Products |
|---|
| Odanacatib
Odanacatib (MK-0822) is a potent and reversible covalent inhibitor of CathepsinK (CatK) with an IC50 of 0.2 nM/1 nM for human/rabbit cathepsin B, L, and S and is highly selective. |
| Cathepsin Inhibitor 1
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. |
| Balicatib
Balicatib is a potent and selective inhibitor of cathepsin K; 10-100-fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S. |
| Loxistatin Acid
Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor. |
| Leupeptin hemisulfate
Leupeptin hemisulfate hemisulfate is the reversible inhibitor of lysosomal serine and cysteine proteinases; Leupeptin; inhibition of cathepsin B(Ki=6 nM), calpain(Ki=10 nM), trypsin (Ki=35 nM), plasmin (Ki=3.4 μM) and kallikrein (Ki=19 μM) had no effect on chymotrypsin, elastase, renin, or pepsin. |
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