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3'-Fluoro-3'-deoxythymidine (Alovudine) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.
| Molecular Weight | 244.22 |
| Formula | C10H13FN2O4 |
| CAS Number | 25526-93-6 |
| Solubility (25°C) | DMSO 49 mg/mL Water 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Lai-Ming Yung, et al. Circ Cardiovasc Imaging. Room With a View
[4] Stefano Rusconi. Curr Opin Investig Drugs. Alovudine Medivir
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