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Alendronic acid

Cat. No. M45244

All AbMole products are for research use only, cannot be used for human consumption.

Alendronic acid Structure
Synonym:

Bisphosphonate

Size Price Availability Quantity
25mg USD 25 In stock
50mg USD 35 In stock
100mg USD 50 In stock
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Biological Activity

Alendronic acid is a bisphosphonate and farnesyl diphosphate synthase (FDPS) inhibitor that inhibits osteoclast-mediated bone resorption. Alendronic acid is used in studies related to postmenopausal osteoporosis, malignant hypercalcemia and Paget's disease.

Chemical Information
Molecular Weight 249.10
Formula C4H13NO7P2
CAS Number 66376-36-1
Form Solid
Solubility (25°C) Water 3.7 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tania A Pawade, et al. Circulation. Effect of Denosumab or Alendronic Acid on the Progression of Aortic Stenosis: A Double-Blind Randomized Controlled Trial

[2] Oula P Medina, et al. Curr Pharm Des. Using Alendronic Acid Coupled Fluorescently Labelled SM Liposomes as a Vehicle for Bone Targeting

[3] Andrew D Duckworth, et al. J Bone Miner Res. Effect of Alendronic Acid on Fracture Healing: A Multicenter Randomized Placebo-Controlled Trial

[4] Tuyen Duong Thanh Nguyen, et al. Sci Rep. Engineered Nanomedicine with Alendronic Acid Corona Improves Targeting to Osteosarcoma

[5] David M Reid, et al. Clin Drug Investig. Alendronic acid produces greater effects than risedronic acid on bone density and turnover in postmenopausal women with osteoporosis : results of FACTS -international

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Keywords: Alendronic acid, Bisphosphonate supplier, inhibitors, activators

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