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Akuammidine

Cat. No. M38964

All AbMole products are for research use only, cannot be used for human consumption.

Akuammidine Structure

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Quality Control & Documentation
Biological Activity

Akuammidine, isolated from the seeds of Picralima nitida, shows a preference for μ-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 μM at μ-, σ- and κ-opioid binding sites, respectively. Akuammidine possesses anti-inflammatory and anti-asthmatic properties.

Chemical Information
Molecular Weight 352.43
Formula C21H24N2O3
CAS Number 639-36-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Rohit Mahar et al. Metabolites. Assessment of Tissue Specific Distribution and Seasonal Variation of Alkaloids in Alstonia scholaris

[2] Wen Chen et al. Nat Commun. Structure units oriented approach towards collective synthesis of sarpagine-ajmaline-koumine type alkaloids

[3] RAYMOND-HAMET. C R Hebd Seances Acad Sci. [On the intestinal effects of akuammidine]

[4] RAYMOND-HAMET. C R Seances Soc Biol Fil. Comparison of the local anesthetic activity of akuammidine with that of cocaine

[5] S Markey et al. Tetrahedron Lett. Isolation of rhazidine and akuammidine from Aspidosperma quebracho blanco. The structure of rhazidine

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Keywords: Akuammidine supplier, Opioid Receptor, inhibitors, activators

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