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AH3960 

Cat. No. M30724

All AbMole products are for research use only, cannot be used for human consumption.

AH3960  Structure

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Quality Control & Documentation
Biological Activity

AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC50 value of 0.82 μM. AH3960 also serves as an agonist of parathyroid hormone receptor-1 (PTHR1).

Chemical Information
Molecular Weight 282.34
Formula C13H22N4O3
CAS Number 862907-48-0
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Percy H Carter, et al. Mol Endocrinol. Actions of the small molecule ligands SW106 and AH-3960 on the type-1 parathyroid hormone receptor

[2] David J Rickard, et al. Bone. Intermittent treatment with parathyroid hormone (PTH) as well as a non-peptide small molecule agonist of the PTH1 receptor inhibits adipocyte differentiation in human bone marrow stromal cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: AH3960  supplier, Androgen Receptor, inhibitors, activators

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