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Agaric acid

Cat. No. M18195

All AbMole products are for research use only, cannot be used for human consumption.

Agaric acid Structure
Synonym:

Agaricinic Acid

Size Price Availability Quantity
5mg USD 22 In stock
10mg USD 35 In stock
20mg USD 45 In stock
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Quality Control & Documentation
Biological Activity

Agaric acid (Agaricinic Acid) is an orally active inhibitor of adenine nucleotide translocase found in specific fungi. Agaric acid can inhibit the biofilm formation of various bacteria such as Salmonella. Agaric acid can also induce mitochondrial permeability transition, prompting mitochondria to release Ca2+, disrupting the transmembrane potential, and causing mitochondrial swelling.

Chemical Information
Molecular Weight 416.55
Formula C22H40O7
CAS Number 666-99-9
Form Solid
Solubility (25°C) DMSO 100 mg/mL
Storage 4°C, protect from light
References

[1] Edmundo Chvez, et al. Biochem Res Int. Interaction of Agaric Acid with the Adenine Nucleotide Translocase Induces Mitochondrial Oxidative Stress

[2] Bram Lories, et al. Biofilm. Agaric acid reduces Salmonella biofilm formation by inhibiting flagellar motility

[3] Noem Garca, et al. Mitochondrion. Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Its dependence on membrane fluidity

[4] R A Freedland, et al. Methods Enzymol. Agaric acid

[5] E Chvez, et al. Life Sci. The effect of agaric acid on citrate transport in rat liver mitochondria

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Keywords: Agaric acid, Agaricinic Acid supplier, Others, inhibitors, activators

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