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Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17. Aderbasib exhibits robust antineoplastic activity and can be used for cancer research, including diffuse large B-cell non-Hodgkin lymphoma, HER2+ breast cancer, gliomas, et al.
| Molecular Weight | 416.47 |
| Formula | C21H28N4O5 |
| CAS Number | 791828-58-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] I GATTO. Blut. [Pernicious anemia in infants (Gerbasi anemia)]
[4] H RIECKE. Arch Kinderheilkd. [Gerbasi's perniciosiform anemia in infants]
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Products are for research use only. Not for human use. We do not sell to patients.
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