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Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist, can ameliorate noise- and cisplatin-induced cochlear injury. Adenosine amine congener (ADAC) mitigates noise-induced hearing loss in a dose- and time-dependent manner, but further studies are required to establish its translation as a clinical otological treatment. Adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity.
| Molecular Weight | 576.60 |
| Formula | C28H32N8O6 |
| CAS Number | 96760-69-9 |
| Solubility (25°C) | DMSO ≥ 10 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
[1] Srdjan M Vlajkovic, et al. Biomed Res Int . Adenosine amine congener as a cochlear rescue agent
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