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Acotiamide dihydrochloride

Cat. No. M9590

All AbMole products are for research use only, cannot be used for human consumption.

Acotiamide dihydrochloride Structure
Synonym:

Z-338 dihydrochloride

Size Price Availability
5mg USD 200 4-7 Days
10mg USD 390 4-7 Days
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Quality Control & Documentation
Biological Activity

Acotiamide is a potent, selective and reversible inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has activity as a muscarinic antagonist. It acts as a prokinetic compound through acetylcholinesterase inhibition and muscarinic receptor antagonism, and has been used for the treatment of functional dyspepsia (FD) involving gastric motility dysfunction.

Chemical Information
Molecular Weight 487.01
Formula C21H30N4O5S.HCl
CAS Number 185104-11-4
Solubility (25°C) Water ≥ 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] K Ito, et al. Dτμg Res (Stuttg). Acotiamide Hydrochloride, a Therapeutic Agent for Functional Dyspepsia, Enhances Acetylcholine-induced Contraction via Inhibition of Acetylcholinesterase Activity in Circular Muscle Strips of Guinea Pig Stomach

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Keywords: Acotiamide dihydrochloride, Z-338 dihydrochloride supplier, AChR/AChE, inhibitors, activators

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