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Aclacinomycin A hydrochloride (Aclarubicin hydrochloride), a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinomycin A hydrochloride is also a dual inhibitor of topoisomerase I and II. An effective anthracycline chemotherapeutic agent for hematologic cancers and solid tumors.
| Molecular Weight | 848.33 |
| CAS Number | 75443-99-1 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
[3] G K Poochikian, et al. Stability of anthracycline antitumor agents in four infusion fluids
[4] S Mori, et al. Physiochemical properties and stability of aclacinomycin A hydrochloride
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