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Acacetin

Cat. No. M4584

All AbMole products are for research use only, cannot be used for human consumption.

Acacetin Structure
Synonym:

5,7-Dihydroxy-4'-methoxyflavone

Size Price Availability Quantity
1mg USD 20 In stock
5mg USD 35 In stock
10mg USD 55 In stock
25mg USD 95 In stock
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Quality Control & Documentation
Biological Activity

Acacetin is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects. Acacetin significantly reduces the Aβ levels by interfering with human APP proteolytic processing and BACE-1 expression. Acacetin inhibited the generation of the APP-CTF by affecting APP cleavage.

Chemical Information
Molecular Weight 284.26
Formula C16H12O5
CAS Number 480-44-4
Solubility (25°C) DMSO: ≥ 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Guangtao Zhang, et al. Acacetin inhibits invasion, migration and TGF-β1-induced EMT of gastric cancer cells through the PI3K/Akt/Snail pathway

[2] Chong Liu, et al. Acacetin Protects Myocardial Cells against Hypoxia-Reoxygenation Injury through Activation of Autophagy

[3] Yao Wu, et al. Acacetin exerts antioxidant potential against atherosclerosis through Nrf2 pathway in apoE -/- Mice

[4] Jos M Di Diego, et al. Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes

[5] Shilpi Singh, et al. Acacetin, a flavone with diverse therapeutic potential in cancer, inflammation, infections and other metabolic disorders

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Keywords: Acacetin, 5,7-Dihydroxy-4'-methoxyflavone supplier, Potassium Channel, inhibitors, activators

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