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Ac-ESMD-CHO

Cat. No. M45314

All AbMole products are for research use only, cannot be used for human consumption.

Ac-ESMD-CHO Structure

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Quality Control & Documentation
Biological Activity

Ac-ESMD-CHO is an inhibitor of caspase-3 and caspase-7 that inhibits the proteolytic cleavage of caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site.

Chemical Information
Molecular Weight 506.53
Formula C19H30N4O10S
CAS Number 191338-87-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Johnson Agniswamy, et al. FEBS J. Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis

[2] Dominique Le Goff, et al. Reprod Toxicol. Apoptotic effects of 25-hydroxycholesterol in immature rat Sertoli cells: prevention by 17beta-estradiol

[3] Z Han, et al. J Biol Chem. A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro

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  Catalog
Abmole Inhibitor Catalog




Keywords: Ac-ESMD-CHO supplier, Caspase, inhibitors, activators

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