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Abeprazan hydrochloride

Cat. No. M29008

All AbMole products are for research use only, cannot be used for human consumption.

Abeprazan hydrochloride Structure
Synonym:

DWP14012 hydrochloride; Fexuprazan hydrochloride

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Quality Control & Documentation
Biological Activity

Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker. Abeprazan hydrochloride inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan hydrochloride is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases.

Chemical Information
Molecular Weight 446.87
Formula C19H18ClF3N2O3S
CAS Number 1902954-87-3
Form Solid
Solubility (25°C) DMSO 25 mg/mL (ultrasonic)
Storage -20°C, dry, sealed
References

[1] Connie Kang. Drugs. Keverprazan Hydrochloride: First Approval

[2] No authors listed. Prasugrel

[3] Lei Zhu, et al. Int Immunopharmacol. Protective effects of berberine hydrochloride on DSS-induced ulcerative colitis in rats

[4] No authors listed. Carteolol

[5] Robert Smyj, et al. Profiles Drug Subst Excip Relat Methodol. Tramadol hydrochloride

Related Proton Pump Products
Omeprazole

Omeprazol is a first-in-class proton pump inhibitor (PPI) used in the treatment of dyspepsia, laryngopharyngeal reflux (LPR) and Zollinger–Ellison syndrome.

Dexlansoprazole

Dexlansoprazole, the dextrorotatory enantiomer of lansoprazole, is a proton pump inhibitor (PPI) formulated to have dual delayed-release properties.

Tenatoprazole

Tenatoprazole is a procompound of the proton pump inhibitor (PPI) class, which inhibits proton transport with IC50 of 3.2 μM.

Esomeprazole Sodium

Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.

Esomeprazole Magnesium

Esomeprazole Magnesium is a proton pump inhibitor to reduce gastric acid secretion.

  Catalog
Abmole Inhibitor Catalog




Keywords: Abeprazan hydrochloride, DWP14012 hydrochloride; Fexuprazan hydrochloride supplier, Proton Pump, inhibitors, activators

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