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Abecarnil (ZK 112119) is a ligand or a partial agonist for benzodiazepine (BZ) receptor. Abecarnil possesses anxiolytic and anticonvulsant properties. Abecarnil can act as a positive allosteric modulator of GABAA receptor. Abecarnil inhibits the binding of the BZ [3H]lormetazepam to rat cerebral cortex membranes, with an IC50 of 0.82 nM. Abecarnil can be used for epilepsy research.
| Molecular Weight | 404.46 |
| Formula | C24H24N2O4 |
| CAS Number | 111841-85-1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Christopher K Gale, et al. BMJ Clin Evid. Generalised anxiety disorder
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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