Free shipping on all orders over $ 500

ABBV-4083

Cat. No. M21659

All AbMole products are for research use only, cannot be used for human consumption.

ABBV-4083 Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

ABBV-4083 is a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.

Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time
Animal Experiment
Animal models microfilariae-positive jirds
Formulation dissolved in 0.5% HPMC/0.02% Tween-80
Dosages 150 mg/kg QD using a volume of 5ml/kg
Administration PO
Chemical Information
Molecular Weight 1024.21
Formula C53H82FNO17
CAS Number 1809266-03-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Alexandra Ehrens, et al. GMS Infect Dis. Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis

[2] Kelly L Johnston, et al. Trends Parasitol. Anti-Wolbachia drugs for filariasis

[3] Marc P Hbner, et al. PLoS Negl Trop Dis. In vivo kinetics of Wolbachia depletion by ABBV-4083 in L. sigmodontis adult worms and microfilariae

[4] Mark J Taylor, et al. Sci Transl Med. Preclinical development of an oral anti- Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis

[5] Thomas W von Geldern, et al. PLoS Negl Trop Dis. Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity

[6] Thomas W von Geldern, et al. PLoS Negl Trop Dis. Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity

Related Anti-infection Products
BTZ043 Racemate

BTZ043 Racemate (BTZ038, BTZ044) is a decaprenylphosphoryl-b-D-ribose 2-epimerase inhibitor.

Cidofovir

Cidofovir (Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis.

Entecavir Monohydrate

Entecavir Hydrate is a class of antiviral compounds.

Oseltamivir

Oseltamivir is a potent and selective inhibitor of influenza virus neuraminidase enzyme.

Zanamivir

Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.

  Catalog
Abmole Inhibitor Catalog




Keywords: ABBV-4083 supplier, Anti-infection, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.